Description

What is 3-CMC (3-Chloromethcathinone)?

3-Chloromethcathinone (commonly abbreviated as 3-CMC or Cloprophedrone) is a synthetic substituted cathinone derivative belonging to the phenethylamine chemical family. Structurally characterized by a chlorine atom substituted at the meta-position of the phenyl ring, 3-CMC serves as a critical halogenated cathinone analog in neuropharmacological bioassays, receptor binding studies, and forensic toxicological screens.

When researchers choose to buy 3-CMC capsules 220mg, they are acquiring pre-measured, micro-encapsulated reference standards designed to bypass manual weighing variance. Each 220mg capsule matrix acts as an encapsulated vessel containing highly purified crystalline material (>99.0% purity threshold), preserving the active molecule against premature atmospheric exposure, oxidation, and humidity-induced degradation during handling.

Unlocking Unrivaled Precision: How 3-CMC 220mg Encapsulation Works

Understanding the precise chemical dynamics of 3-Chloromethcathinone requires evaluating its molecular structure and kinetic performance under controlled laboratory conditions. The incorporation of a halogen atom (chlorine) into the aromatic ring significantly alters the molecule’s lipophilicity, enzymatic resistance, and binding kinetics compared to non-halogenated Cathinone analogs such as 3-MMC or 4-MMC.

Key Chemical Specifications & Molecular Architecture

• Systematic IUPAC Name: 1-(3-chlorophenyl)-2-(methylamino)propan-1-one hydrochloride

• CAS Registry Number: 1607439-32-6

• Molar Mass: 197.66 g/mol (free base) / 234.12 g/mol (hydrochloride salt)

• Purity Standard: ≥99.0% verified via HPLC and 1H-NMR analysis

• Encapsulated Matrix: Gelatin/HPMC shell containing exactly 220mg active material (±0.2% tolerance)

In analytical assays, 3-CMC acts primarily as a monoamine transporter substrate. In vitro models demonstrate its capacity to interact with dopamine transporters (DAT), norepinephrine transporters (NET), and serotonin transporters (SERT), altering extracellular neurotransmitter accumulation. The 220mg encapsulated format yields a predictable molar concentration when dissolved in standard analytical solvents (such as methanol, acetonitrile, or phosphate-buffered saline), enabling seamless calibration for High-Performance Liquid Chromatography (HPLC) and Gas Chromatography-Mass Spectrometry (GC-MS) runs.

Essential Advantages of Pre-Dosed 220mg Encapsulated Standards

Handling bulk crystalline powder introduces airborne particulate hazards, static interference during weighing, and inevitable analytical variance across multi-run research protocols. Utilizing pre-measured 220mg capsules offers several critical methodological benefits:

1. Elimination of Mass Measurement Variance: Bypasses manual micro-balance calibration steps, guaranteeing precisely 220mg of substrate per analytical run.

2. Reduced Airborne Contamination Risk: Encapsulation prevents volatile dust emission, protecting lab environments and personnel from unexpected exposure.

3. Enhanced Hydrolytic Protection: The sealed encapsulation protects the hygroscopic hydrochloride salt from ambient humidity and oxidative breakdown.

4. Optimal Solubilization Calibration: Designed to dissolve completely in standard assay buffers, producing exact, repeatable volumetric concentrations.

Target Research Applications: Who Uses 3-CMC Capsules 220mg?

Our reference materials are supplied strictly to accredited research institutions, analytical laboratories, forensic authorities, and toxicological researchers. Primary investigative domains include:

• Neuropharmacology Laboratories: Evaluating monoamine reuptake inhibition profiles and monoamine transporter binding affinities in cell culture models.

• Forensic & Toxicological Screening: Developing exact baseline retention indices, mass spectra fragmentation patterns, and metabolic identification matrices.

• Medicinal Chemistry Teams: Conducting structure-activity relationship (SAR) studies comparing halogenated cathinones against non-halogenated substituted phenethylamines.

• Comparative Chemical Profiling: Benchmark comparative testing against structurally adjacent reagents like 2-FMA Powder and 2F-Ketamine Crystal-powder.